What is simvastatin 80 mg used for?
Facts about simvastatin Used together with diet and exercise to reduce the amount of low-density lipoprotein (LDL) cholesterol (“bad cholesterol”) in the blood to decrease the risk of heart attack, stroke, and cardiovascular death. The 80-mg dose lowers the LDL cholesterol by an additional 6% over simvastatin 40 mg.
What are the side effects of simvastatin 80 mg?
The more common side effects that can occur with simvastatin include:
- headache.
- nausea.
- stomach pain.
- constipation.
- muscle pain or weakness.
- joint pain.
- upper respiratory infections.
Is simvastatin good for your heart?
Statins don’t just lower cholesterol levels but also reduce the risk of fatty plaques breaking off from walls of your arteries, reducing the risk of heart attack and stroke. Some people may be able to reduce their cholesterol to safe levels by changing their diet, or exercising more.
When do I take simvastatin 80 mg?
How to use Simvastatin. Take this medication by mouth as directed by your doctor, usually once daily in the evening. If you are using the tablet form of this medication, you may take this medication with or without food. If you are using the liquid form of this medication, take this medication on an empty stomach.
Does simvastatin cause liver damage?
Rare cases of acute liver failure and death have been attributed to simvastatin. But in view of the wide use of simvastatin, clinically apparent liver injury is exceeding rare and is estimated to occur in 1 per 100,000 patient years of exposure.
What should you avoid while taking simvastatin?
Drinking large amounts of grapefruit juice (more than 1 quart each day) while taking this medicine may increase your risk of muscle injury and could result in kidney problems. Do not drink large amounts of alcohol with simvastatin. This could cause unwanted effects on the liver.
Is 80mg of statin high?
What is already known? High dose statins (40mg and 80 mg atorvastatin) are important in reducing ASCVD events. However, these high statin doses are associated with increased adverse effects like liver enzyme elevation, new onset diabetes mellitus and myalgia/myopathy which are related to dose.
Can simvastatin cause sleep problems?
The top-selling statins are atorvastatin (Lipitor), lovastatin (Mevacor), rosuvastatin (Crestor) and simvastatin (Zocor). How they can cause insomnia: The most common side effect of all types of statins is muscle pain, which can keep people who take them awake at night and unable to rest.
How many patients are prescribed Simvastatin 80 mg?
It is estimated that approximately 2.1 million patients in the U.S. were prescribed a product containing 80-mg simvastatin in year 2010. Patients taking simvastatin 80 mg daily have an increased risk of myopathy compared to patients taking lower doses of this drug or other drugs in the same class.
How effective is simvastatin for lipid control?
More patients on simvastatin withdrew from treatment as a result of inefficacy (49.3% vs. 23.2%, p = 0.025) compared with the atorvastatin group. Furthermore, patients on simvastatin were more likely to be failing conventional targets of lipid control, compared with patients on atorvastatin 80 mg (43.5% vs. 21.3%, p = 0.006).
What is atorvastatin 80 mg used for?
Atorvastatin 80 mg is a well-established treatment option for high-risk individuals following the demonstration of its superior efficacy in the PROVE-IT (compared with pravastatin 40 mg) ( 10) and TNT (compared with atorvastatin 10 mg) ( 11) studies.
Is there a generic version of simvastatin?
In addition to these new limitations, FDA is requiring changes to the simvastatin label to add new contraindications (should not be used with certain medications) and dose limitations for using simvastatin with certain medicines. Sold as a single-ingredient generic medication and under the brand-name Zocor.
